The work of clinical genomics doesn’t end with the first report. ClinVar reclassifies, literature evolves, a variant once called uncertain significance may, two years later, be called pathogenic. Today, that follow-up is mostly an inbox problem. Ocean Clinic turns it into a worklist.

The service runs the same reinterpretation queries a lab already runs once at report time — except it keeps running them, every week, against every variant in every report the practice has ever issued. When a variant’s classification shifts, the case lands in the responsible clinician’s queue with full context: which classification changed, on whose report, what it is now, and how confident the new call is.

The decision — amend, acknowledge, defer, dismiss — is recorded with reason, signed, and added to the audit trail. The platform handles the bookkeeping; the clinician handles the medicine.

The disposition of the service: notice the variant, then get out of the clinician’s way.

Ocean Clinic is built on Ocean, our genomic data ecosystem. Clinic deploys can be served via AWS or self-hosted, depending on the partner’s needs. Clinics serving rare-variant patient populations may choose to opt in to Ocean Research, nascnt's tool for enabling anonymized cross-institution research across the collective case data of all Ocean Clinic partners. Research is a separate venture, currently in development.

We’re running a small number of pilot partnerships with clinical labs and counseling practices through 2026. Each pilot includes white-glove ingest of existing case data, a synthetic-environment shakedown of the worklist with your team, and weekly clinical review during the first quarter.